@article {25, title = {Predictors of clinical success in runners with patellofemoral pain: Secondary analyses of a randomized clinical trial.}, journal = {J Sci Med Sport}, year = {2018}, month = {2018 Jan 27}, abstract = {

OBJECTIVES: To identify predictors of outcome to a rehabilitation program focused on education and management of training loads in runners with patellofemoral pain (PFP).

DESIGN: Secondary analyses of a randomized clinical trial.

METHODS: Fifty-eight runners with PFP (62\% female, aged 31.2{\textpm}6.6years, running 20.3{\textpm}5.6km/week) were included in analyses. Following baseline collection of demographics, anthropometry, symptomatology, isometric strength, running mechanics and radiological data, runners were randomized to one of the three 8-week intervention program: (1) Education on symptoms management and training modifications; (2) Education+Exercise program; (3) Education+Gait retraining. Clinical success was defined as an increase >=13.6\% on the Knee Outcome Survey - Activities of Daily Living Scale (KOS-ADLS) at 3 months following program completion. Potential predictors were entered into logistic regression analyses.

RESULTS: Forty-five runners (78\%) were categorized as Success. Together, KOS-ADLS score (<70\%), knee extension isometric strength (<70\% bodyweight), presence of patellar tendinopathy (Grade >0) and level of usual pain (>2/10) at baseline predicted treatment outcome with 87.9\% accuracy. The model provided sensitivity of 0.93 (95\% C.I. 0.82-0.98), specificity of 0.69 (95\% C.I. 0.42-0.87), positive likelihood ratio of 3.0 (95\% C.I. 1.3-6.9), and negative likelihood ratio of 0.1 (95\% C.I. 0-0.3). The best individual predictors were KOS-ADLS score and knee extension strength.

CONCLUSIONS: The combination of KOS-ADLS, knee extensors strength, patellar tendon integrity and usual pain best predicted clinical outcome of runners with PFP following an intervention that had a common education component. Further testing is needed before a clinical prediction rule can be recommended to clinicians.

}, issn = {1878-1861}, doi = {10.1016/j.jsams.2018.01.006}, author = {Esculier, Jean-Fran{\c c}ois and Bouyer, Laurent J and Dubois, Blaise and Leblond, Jean and Brisson, M{\'e}lanie and Chau, Luc and Roy, Jean-S{\'e}bastien} }